Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Most CBT Delivery Methods Effective for Depression

Key clinical point: Regardless of the delivery method, most forms of cognitive-behavioral therapy are effective for improving the severity of depression.

Major finding: Individual, group, telephone, and guided self-help cognitive-behavioral therapy all achieve significant improvements in depression, compared with controls.

Study details: A network meta-analysis of 155 trials involving 15,191 participants.

Disclosures: Two authors reported receiving personal fees from private industry outside of the submitted work. One reported receiving grants and support from the National Institute for Health Research.


Cuijpers P, et al. JAMA Psychiatry. 2019 Apr 17. doi:10.1001/jamapsychiatry.2019.0268.