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Depression, MetS Linked in Older Latinos with Diabetes

Am J Geriatr Psychiatry; ePub 2017 Feb 23; Cardenas, et al

Depression is significantly linked to metabolic syndrome (MetS), and most notably dyslipidemia, in older Latinos with diabetes, a recent study found. 332 community-dwelling older (aged ≥60 years) Latinos with type 2 diabetes completed the 9-item Patient Health Questionnaire (PHQ-9) and received a health check-up assessing Body Mass Index (BMI), triglyceride and high-density lipoprotein (HDL) cholesterol levels, and blood pressure. Logistic regression analysis compared MetS rates of those meeting criteria for depression to those who did not. Secondary analyses examined the associations between depression and individual MetS components. All analyses controlled for demographic (eg, income, age) and other potential MetS risk factors (eg, smoking status, physical activity, and alcohol consumption). Researchers found:

  • Depression was significantly associated with an increased risk of MetS, as well as clinically significant elevations in triglycerides and reduced (HDL) cholesterol.
  • A significant association was not observed between depression and either BMI or hypertension.


Cardenas V, Mausbach BT, Sommerfeld D, et al. Depression is associated with increased risk for metabolic syndrome in Latinos with type 2 diabetes. [Published online ahead of print February 23, 2017]. Am J Geriatr Psychiatry. doi:10.1016/j.jagp.2017.02.017.