Clinical Edge

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COVID-19 could be asymptomatic in 40%-45% of infected

Key clinical point: Asymptomatic cases of COVID-19 may be “a significant factor” in the spread of SARS-CoV-2.

Major finding: Between 40% and 45% of COVID-19 cases may be in individuals who are completely asymptomatic as opposed to presymptomatic.

Study details: An analysis of 16 cohorts of individuals with COVID-19 cases.

Disclosures: The authors and Dr. Trueger reported no relevant conflicts of interest.


Oran DP, Topol EJ. Ann Intern Med. 2020 Jun 3. doi: 10.7326/M20-3012.