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Mood Symptoms and Suicidality in Bipolar Disorder

Suicide Life Threat Behav; ePub 2018 Nov 19; Kamali, et al

While dimensions of personality, trauma, and substance use clearly correlated with suicidal behaviors in bipolar disorder (BD), in multivariate models emerging mood symptoms were the most robust predictors of suicidality, a recent study found. These results reinforce the importance and attributable role of mood and anxiety symptoms in evaluating suicidal risk. Mood, personality, and clinical features were assessed in 151 individuals with BD I and 119 healthy controls (HC). Clinical data were collected at baseline and at 2‐year follow‐up. Researchers found:

  • In bivariate analyses, personality measures were significantly different between BD and HC, and between BD based on suicide attempt history.
  • However, in regression analyses, baseline measures of depression, mania, anxiety, trauma, education, and age of BD onset correlated with personality domains, while a history of suicide attempts did not.
  • Logistic regressions showed that prospective depression or mania, and a pattern of mixed mood features and chronicity of illness, along with two Neuroticism facet scores (N4—Self‐Consciousness and N6—Vulnerability) were predictive of suicide ideation (SI) in the 2‐year follow‐up period.

Kamali M, Saunders EFH, Assari S, Ryan KA, Marshall DF, McInnis MG. Mood, dimensional personality, and suicidality in a longitudinal sample of patients with bipolar disorder and controls. [Published online ahead of print November 19, 2018]. Suicide Life Threat Behav. doi:10.1111/sltb.12529.

This Week's Must Reads

Cognition Impairment a Familial Disposition of MDD, JAMA Psychiatry; ePub 2018 Dec 26; Mackenzie, et al

Cognition in MDD and Aberrant Network Connectivity, J Psychiatr Res; 2019 Mar; Albert, Potter, Boyd, et al

Partner Criticism During Therapy for Recurrent MDD, Behav Res Ther; ePub 2018 Dec 21; Vittengl, et al

Study: Predictions of MDD Are Multifactorial, Depress Anxiety; ePub 2018 Dec 5; van Bronswijk, et al

Linguistic Analysis of Memories of People with MDD, PLoS One; ePub 2018 Nov 26; Himmelstein, et al

Must Reads in Bipolar Disorder

BD Course Strongly Affected by Comorbid Disorders, J Affect Disord; ePub 2018 Dec 25; Weintraub, et al

Differentiating Borderline Personality from BD, Compr Psychiatry; 2019 Jan; Balling, et al

Bipolar Diathesis in Major Depression Disorder , J Affect Disord; ePub 2018 Nov 2; Bennett, et al

Expressed Emotion Among Parents of Youths with BD, Psychiatry Res; 2018 Dec; Millman, Weintraub, et al

Predicting Risk of Conversion from Mania to BD I/II , J Am Acad Child Adolesc Psychiatry; 2018 Oct; Birmaher, et al