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Differentiating Borderline Personality from BD

Compr Psychiatry; 2019 Jan; Balling, et al

Within a sample of depressed patients, the Mood Disorder Questionnaire (MDQ) triad is a better screener for bipolar disorder (BD) than the full MDQ, particularly if a positive triad screen is indicated by the presence of any 2 items, according to a recent study. The triad is particularly good for differentiating between BD and borderline personality disorder (BPD), whereas the full MDQ does a poorer job of differential diagnosis. Patients presenting for treatment were assessed with the Structured Clinical Interview for DSM-IV (SCID) and the BPD module of the Structured Interview for DSM-IV Personality (SIDP-IV). The present report is based on 476 depressed patients who had a principal diagnosis of major depressive disorder (MDD) or BD and who completed the MDQ. Researchers found:

  • 57 patients were diagnosed with BD and 54 patients were diagnosed with BPD.
  • Both the triad and full MDQ significantly predicted BD diagnosis, but the triad had optimal operating characteristics, particularly at a cut-off of 2.

Balling C, Chelminski I, Dalrymple K, Zimmerman M. Differentiating borderline personality from bipolar disorder with the Mood Disorder Questionnaire (MDQ): A replication and extension of the International Mood Network (IMN) Nosology Project. Compr Psychiatry. 2019;88:49-51. doi:10.1016/j.comppsych.2018.11.009.