Within a sample of depressed patients, the Mood Disorder Questionnaire (MDQ) triad is a better screener for bipolar disorder (BD) than the full MDQ, particularly if a positive triad screen is indicated by the presence of any 2 items, according to a recent study. The triad is particularly good for differentiating between BD and borderline personality disorder (BPD), whereas the full MDQ does a poorer job of differential diagnosis. Patients presenting for treatment were assessed with the Structured Clinical Interview for DSM-IV (SCID) and the BPD module of the Structured Interview for DSM-IV Personality (SIDP-IV). The present report is based on 476 depressed patients who had a principal diagnosis of major depressive disorder (MDD) or BD and who completed the MDQ. Researchers found:
- 57 patients were diagnosed with BD and 54 patients were diagnosed with BPD.
- Both the triad and full MDQ significantly predicted BD diagnosis, but the triad had optimal operating characteristics, particularly at a cut-off of 2.
Balling C, Chelminski I, Dalrymple K, Zimmerman M. Differentiating borderline personality from bipolar disorder with the Mood Disorder Questionnaire (MDQ): A replication and extension of the International Mood Network (IMN) Nosology Project. Compr Psychiatry. 2019;88:49-51. doi:10.1016/j.comppsych.2018.11.009.
Must Reads in Bipolar Disorder
BD Course Strongly Affected by Comorbid Disorders, J Affect Disord; ePub 2018 Dec 25; Weintraub, et al
Motor Activity, Energy, Mood, Sleep Examined in BD, JAMA Psychiatry; ePub 2018 Dec 12; Merikangas, et al
Differentiating Borderline Personality from BD, Compr Psychiatry; 2019 Jan; Balling, et al
Bipolar Diathesis in Major Depression Disorder , J Affect Disord; ePub 2018 Nov 2; Bennett, et al
Expressed Emotion Among Parents of Youths with BD, Psychiatry Res; 2018 Dec; Millman, Weintraub, et al