Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Differentiating Borderline Personality from BD

Compr Psychiatry; 2019 Jan; Balling, et al

Within a sample of depressed patients, the Mood Disorder Questionnaire (MDQ) triad is a better screener for bipolar disorder (BD) than the full MDQ, particularly if a positive triad screen is indicated by the presence of any 2 items, according to a recent study. The triad is particularly good for differentiating between BD and borderline personality disorder (BPD), whereas the full MDQ does a poorer job of differential diagnosis. Patients presenting for treatment were assessed with the Structured Clinical Interview for DSM-IV (SCID) and the BPD module of the Structured Interview for DSM-IV Personality (SIDP-IV). The present report is based on 476 depressed patients who had a principal diagnosis of major depressive disorder (MDD) or BD and who completed the MDQ. Researchers found:

  • 57 patients were diagnosed with BD and 54 patients were diagnosed with BPD.
  • Both the triad and full MDQ significantly predicted BD diagnosis, but the triad had optimal operating characteristics, particularly at a cut-off of 2.
Citation:

Balling C, Chelminski I, Dalrymple K, Zimmerman M. Differentiating borderline personality from bipolar disorder with the Mood Disorder Questionnaire (MDQ): A replication and extension of the International Mood Network (IMN) Nosology Project. Compr Psychiatry. 2019;88:49-51. doi:10.1016/j.comppsych.2018.11.009.

This Week's Must Reads

Risk of PTSD and MDD Following Mild TBI, JAMA Psychiatry; ePub 2019 Jan 30; Stein, et al

CBT Improves Depressive Symptoms in PD, Int J Geriatr Psych; ePub 2019 Feb 4; Dobkin, et al

Bullying in Late Adolescence and Depression Risk , Behav Brain Res; ePub 2019 Jan 30; Graziano, et al

Shifting and Focusing Examined in Clinical Sample, J Affect Disord; 2019 Apr 1; Hsu, Forgeard, et al

BPD in Medication-Free Young Subjects with MDD, J Psych Res; 2019 Mar; Koirala, Hu, et al

Must Reads in Bipolar Disorder

BD Course Strongly Affected by Comorbid Disorders, J Affect Disord; ePub 2018 Dec 25; Weintraub, et al

Motor Activity, Energy, Mood, Sleep Examined in BD, JAMA Psychiatry; ePub 2018 Dec 12; Merikangas, et al

Differentiating Borderline Personality from BD, Compr Psychiatry; 2019 Jan; Balling, et al

Bipolar Diathesis in Major Depression Disorder , J Affect Disord; ePub 2018 Nov 2; Bennett, et al

Expressed Emotion Among Parents of Youths with BD, Psychiatry Res; 2018 Dec; Millman, Weintraub, et al