Clinical Edge

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CBT by phone reduces depression in Parkinson’s disease

Key clinical point: Telephone-based cognitive behavioral therapy (CBT) significantly improves depression, anxiety, and quality of life in patients with Parkinson’s disease, relative to usual care.

Major finding: Post treatment, mean improvement in Hamilton Depression Rating Scale score from baseline was 6.53 points in the telephone-based CBT group, compared with −0.27 points in the control group.

Study details: A randomized controlled trial that assigned 72 patients with Parkinson’s disease to usual care plus telephone-based CBT or usual care only.

Disclosures: The trial was funded by the Michael J. Fox Foundation for Parkinson’s Research and the Parkinson’s Alliance (Parkinson’s Unity Walk).


Dobkin RD et al. Neurology. 2020 Apr 1. doi: 10.1212/WNL.0000000000009292.