Clinical Edge

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Smoking Cessation and Serious Mental Illness

Drug Alcohol Depend; 2018 Jan; Hammett, et al

Quitting smoking was not associated with heightened binge drinking or symptoms of depression and anxiety among smokers with serious mental illness (SMI), a recent study found. This study is a secondary analysis of the OPTIN trial, which demonstrated the effectiveness of proactive outreach for smoking cessation among Minnesota Health Care Programs enrollees. Participants with ICD-9 codes indicating schizophrenia spectrum disorders, psychotic disorders, bipolar disorders, or severe/recurrent major depressive disorder were categorized as having SMI (n=939); remaining smokers were categorized as non-SMI (n=1,382). Multivariable regressions modeled the association between incident smoking cessation and binge drinking, PHQ-2 depression scores, and PROMIS anxiety scores in the 2 groups. Researchers found:

  • Quitting smoking was not associated with binge drinking among those with SMI, but was associated with less binge drinking among those without SMI.
  • Quitting smoking was not associated with PHQ-2 depression scores among those with or without SMI.
  • However, quitting smoking was associated with lower mean PROMIS anxiety scores for those with SMI, but not those without SMI.

Citation:

Hammett PJ, Lando HA, Taylor BC, et al. The relationship between smoking cessation and binge drinking, depression, and anxiety symptoms among smokers with serious mental illness. Drug Alcohol Depend. 2019;194:128-135. doi:10.1016/j.drugalcdep.2018.08.043.

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