Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Serious Mental Illness Linked with Violent Behavior

J Interpers Violence; ePub 2018 Mar 13; Roche, et al

Patients with serious mental illness (SMI) conditions had higher rates of violent ideation and behavior (VIS) than both patients with non-SMI psychopathology and those with substance use disorders (SUDs) only, according to a recent study. Researchers analyzed the intake records of 63,572 patients diagnosed with SMIs (ie, schizoaffective disorder, schizophrenia, bipolar disorder, and unipolar depression), SUDs, and non-SMI psychiatric disorders. Raw prevalence rates for a combined metric of VIS were established and compared for each group, and a series of logistic regression analyses were performed to estimate how various demographic factors influenced the likelihood of VIS endorsement in each study group. They found:

  • Patients with SMI and comorbid substance use pathology were responsible for the majority of VIS with in each SMI condition.
  • Men with SMI conditions had higher prevalence rates of VIS than females.
  • In addition, for every SMI diagnosis, comorbid SUDs and younger age were related to greater risk for VIB, and where race and gender were found to significantly alter the likelihood of VIS endorsement, African American status, and female gender were independently related to greater risk.


Roche MW, Boyle OJ, Cheng C-C, et al. Prevalence and risk of violent ideation and behavior in serious mental illnesses: An analysis of 63,572 patient records. [Published online ahead of print March 13, 2018]. J Interpers Violence. doi:10.1177/0886260518759976.

This Week's Must Reads

Public Perception of Female Fertility Examined, Arch Sex Behav; 2018 Jul; Jensen, Martins, et al

Sleep Debt, Daytime Sleepiness, and Mental Health, Depress Anxiety; ePub 2018 May 22; Dickinson, et al

Ethnic Differences in Diagnosis of Schizophrenia, Psychiatry Res; ePub 2018 May 30; Hamilton, et al

Denial of Service Laws, Mental Distress Linked, JAMA Psychiatry; ePub 2018 May 23; Raifman, et al

Distress Tolerance: Stress Buffer for Firefighters?, Psychiatry Res; ePub 2018 May 24; Stanley, et al

Must Reads in Addiction Medicine

Mixed Review for Facebook Smoking Intervention, Addiction; ePub 2018 May 24; Ramo, Thrul, et al

Young Adult Alcohol Use and Romantic Relationships, Subst Use Misuse; ePub May 8; Fleming, Lee, et al

FDA Approves Lucemyra for Opioid Withdrawal, FDA Web site; 2018 May 16

Caffeine May Promote Early Use of Other Substances, Addiction; ePub 2018 Apr 30; Krisjansson, et al

Prescription Stimulant Use, Misuse, and Motivations, Am J Psychiatry; ePub 2018 Apr 16; Compton, et al