Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Electronic Nicotine System Use and Mental Health

Addiction; ePub 2018 Oct 6; Spears, et al

In 2017, US adults with vs without mental health conditions (MHC) were more likely to use electronic nicotine delivery systems (ENDS), according to a recent study. In particular, both never and current smokers with MHC reported disproportionately high rates of current ENDS use. A total of 5,762 adults (52.0% female; 64.8% non‐Hispanic white, 11.4% non‐Hispanic black, 15.9% Hispanic, 7.9% non‐Hispanic other) participated in a cross‐sectional, nationally representative survey. Researchers found:

  • Lifetime MHC and past‐month serious psychological distress (SPD) were each associated with higher likelihood of having ever used ENDS, currently using ENDS, and currently using ENDS daily.
  • There were interactions between MHC and smoking status in predicting ENDS use, such that MHC status predicted higher lifetime and current ENDS use specifically among never and current smokers.
  • Never smokers with MHC had 2.62 higher odds of current ENDS use than those without MHC.
  • Among never smokers, those with MHC indicated higher expectations that ENDS would improve relaxation and concentration.


Spears CA, Jones DM, Weaver SR, Yang B, Pechacek TF, Eriksen MP. Electronic nicotine delivery system (ENDS) use in relation to mental health conditions, past‐month serious psychological distress and cigarette smoking status, 2017. [Published online ahead of print October 6, 2018]. Addiction. doi:10.1111/add.14464.

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