Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Must Reads by Date

Must reads for theWeek ending February 21, 2016

Depression Screening in Children and Adolescents , USPSTF updates its recommendation

Predicting Negative & Unusually Positive Outcomes , Pretreatment symptom levels can help

Executive System Dysfunction in Young People, Impact on various psychiatric disorders evaluated

Abnormal Eating in Patients with Alzheimer , Link seen in this specific type of dementia

Buprenorphine-Samidorphan Combination for MDD, Evaluated as adjunct when standard therapy fails

More must reads

Must reads for theWeek ending February 14, 2016

Depression Symptoms in Teens Usually Treated, but…, …follow-up is low and treatment quality varies

Impact of GABA Level on Antipsychotics, Measures referenced to creatine or water evaluated

Genetic Variants May Predict Response to Lithium , Carriers of 4 alleles had lower relapse rates

Benzodiazepines and Cognitive Decline Risk, Various rates of usage evaluated vs non-use

Diet’s Impact on Sleep Arousals & Slow Wave Sleep , Fiber and saturated fat could play a role

More must reads

Must reads for theWeek ending February 7, 2016

Adzenys XR-ODT Approved to Treat ADHD , Extended-release orally disintegrating tablet

Team-Based Approach for First Episode Psychosis, How did it compare to usual community care?

3 Smoking Cessation Approaches Evaluated , Randomized trial shows no substantial differences

Autism and Intellectual Disabilities, These maternal factors seem to elevate risk

Low-dose Buprenorphine in Suicide-Prone Patients , Adjunctive use shows promise, with no withdrawal

More must reads

Must reads for theWeek ending January 31, 2016

USPSTF Recommends Depression Screening in All Adults, Suggestions for women during and after pregnancy

Type 2 Diabetes and Antipsychotic Use, Meta-analysis evaluates prevalence in youths

Racial-ethnic Disparities and Psychosis , Evidence seen in subthreshold subtypes

Predicting Bipolar Disorder in High-Risk Youths, Sleep disturbance may be a prognostic indicator

Citalopram in Patients with Alzheimer Disease, Use should be limited to certain patients

More must reads

Must reads for theWeek ending January 24, 2016

Prognosis of Brief Psychotic Episodes, Does recurrence risk differ between types?

Mental Illness in Offspring of Patients with BD , Higher rates seen in US children

Impact of Early Depression Later in Childhood, Trajectory of cortical gray matter evaluated

The Prevalence of Drug Use Disorder, 12-month and lifetime risk evaluated

Mental Disorders and Chronic Conditions , Link to onset of 10 physical illnesses evaluated

More must reads