Clinical Edge

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Psoriasis Ointment Helped With Itch, Healing in Phase 2 EB Study

Key clinical point: Low-dose calcipotriol ointment significantly improved wound healing and itch in people with recessive dystrophic epidermolysis bullosa (RDEB).

Major finding: A greater percentage of wound size reduction was observed after 2 weeks when the ointment was applied (88.4% vs. 65.5% for placebo; P less than .006).

Study details: A phase 2, randomized, double-blind, two-arm, placebo-controlled study of nine adults with RDEB.

Disclosures: The study was funded by DEBRA Austria. The presenting author, Dr. Guttmann-Gruber had no conflicts of interest to disclose.


Guttmann-Gruber C et al. EB World Congress 2020. Poster 34.