Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Organ Transplants Carry Risk of Several Cancers

Pediatrics; 2017 May; Yanik, et al

Children who receive organ transplants are far more likely to develop many types of cancer, according to a US transplant registry that was linked to 16 cancer registries. The investigation revealed the following results:

  • 392 cancers were diagnosed among nearly 18,000 children who had received solid organ transplantation.
  • The standardized incidence ratio (SIR) for non-Hodgkin’s lymphoma was significantly increased when compared to the general public.
  • Other cancers that occurred more frequently among transplant recipients included leukemia, myeloma, and cancers of the liver, ovaries, and testes.

Citation:

Yanik EL, Smith JM, Shiels MS, et al. Cancer risk after pediatric solid organ transplantation. Pediatrics. 2017;139:e20163893. doi:10.1542/peds.2016-3893.

This Week's Must Reads

Water Fluoridation and Income-Related Dental Caries, JAMA Pediatrics; ePub 2019 Jan 28; Sanders, et al

Trends in Pediatric Hospitalizations, Readmissions, Pediatrics; ePub 2019 Jan 29; Bucholz, et al

High Cost of Home Respiratory Equipment, Supply Use, J Pediatr; ePub 2019 Jan 4; Berry, Goodman, et al

Truncal-to-Leg Ratio and Cardiometabolic Disease, Pediatr Obes; ePub 2019 Jan 25; Cioffi, et al

Pediatric Antibiotic Prescribing in US EDs Examined, Pediatrics; ePub 2019 Jan 8; Poole, Shapiro, et al

Must Reads in Oncology

Organ Transplants Carry Risk of Several Cancers, Pediatrics; 2017 May; Yanik, et al