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Organ Transplants Carry Risk of Several Cancers

Pediatrics; 2017 May; Yanik, et al

Children who receive organ transplants are far more likely to develop many types of cancer, according to a US transplant registry that was linked to 16 cancer registries. The investigation revealed the following results:

  • 392 cancers were diagnosed among nearly 18,000 children who had received solid organ transplantation.
  • The standardized incidence ratio (SIR) for non-Hodgkin’s lymphoma was significantly increased when compared to the general public.
  • Other cancers that occurred more frequently among transplant recipients included leukemia, myeloma, and cancers of the liver, ovaries, and testes.

Citation:

Yanik EL, Smith JM, Shiels MS, et al. Cancer risk after pediatric solid organ transplantation. Pediatrics. 2017;139:e20163893. doi:10.1542/peds.2016-3893.