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Cerebral blood flow may predict children’s recovery from persistent postconcussion symptoms

Key clinical point: Cerebral blood flow shows promise as a predictive biomarker in children with persistent postconcussion symptoms.

Major finding: Cerebral blood flow at 4-6 weeks post injury predicts subsequent recovery in 77% of children.

Study details: An analysis of data for 61 children who participated in the randomized controlled Play Game trial of melatonin for persistent postconcussion symptoms.

Disclosures: The Alberta Children’s Hospital, the Canadian Institutes of Health Research, and the University of Calgary funded the study. Dr. Barlow had no disclosures or conflicts of interest.


Barlow K et al. CNS-ICNA 2020. Abstract PL100.