Key clinical point: A next-generation sequencing test for pathogen detection demonstrated higher sensitivity than conventional testing methods in a cohort of pediatric patients.
Major finding: The Karius test detected pathogens with 92% sensitivity, compared with 64% sensitivity for all conventional testing methods combined (P less than .01).
Study details: A retrospective analysis of 100 test results in 79 pediatric patients.
Disclosures: The researchers did not receive any funding for this study, but they were previously involved in a study funded by Karius, the company that commercialized the test.
Rossoff J et al. ASPHO 2019, Abstract 439.