Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Study supports halting antiseizure medications after neonatal seizures

Key clinical point: Halting antiseizure medications is safe after acute symptomatic neonatal seizures.

Major finding: Functional development measures were similar with discontinued and maintenance therapy.

Study details: Prospective, observational, comparative effectiveness study of 270 patients at nine centers enrolled in the Neonatal Seizure Registry.

Disclosures: The study was funded by the Patient-Centered Outcomes Research Institute (PCORI) and the Pediatric Epilepsy Research Foundation. Dr. Glass has no other financial relationships to disclose.


Glass HC et al. CNS-ICNA 2020. Presentation PL58.