Clinical Edge

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Low–Glycemic-Index Diet Effective for Seizure Reduction

Key clinical point: Sticking to a low–glycemic-index diet (LGID) for 5 days per week was as effective as the stricter standard daily version and was preferred by caregivers and patients.

Major finding: The mean reduction in weekly seizure frequency was 54% in the strict LGID group and not significantly different at 49% in the intermittent LGID patients.

Study details: This was a randomized, double-blind, 24-week, noninferiority study involving 122 children aged 1-15 years with drug-refractory epilepsy.

Disclosures: The presenter reported having no financial conflicts regarding the study, sponsored by the All India Institute of Medical Sciences.


Panda PK et al. IEC 2019, Abstract P056.