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Incidence of CNS tumors appears lower in Chinese children

Key clinical point: The incidence of central nervous system (CNS) tumors appears lower in Chinese children compared with children of Asian/Pacific Islander descent and children of all ethnicities in the United States.

Major finding: Adjusted incidence rates of CNS tumors were significantly higher in the U.S. cohorts than in the cohort of children from Hong Kong (P < .001). The rates were 2.51 per 100,000 in the Hong Kong cohort, 3.26 per 100,000 in the U.S. Asian/Pacific Islander cohort, and 4.10 per 100,000 in the U.S. cohort including all ethnicities.

Study details: A population-based cohort study including 508 Hong Kong patients of Chinese descent, 447 U.S. patients of Asian/Pacific Islander descent, and 5,047 U.S. patients of any ethnicity, all with CNS tumors.

Disclosures: The study was supported by the American Lebanese Syrian Associated Charities and the Children’s Cancer Foundation, Hong Kong. The authors disclosed affiliations with MSD Oncology, Genentech, and Kazia.


Liu APY et al. JCO Glob Oncol. 2020 May 11. doi: 10.1200/JGO.19.00378.