Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Obesity and Dyslipidemia in Children With Atopic Dermatitis

Compared with age-matched healthy controls, the prevalence of overweight, obesity, and dyslipidemia is greater in children with atopic dermatitis (AD), a new study found. The prospective, cross-sectional study included 239 children aged <14 years. Researchers found:

  • Mean body mass index (BMI) was slightly higher in patients with AD vs healthy controls and significantly higher in patients with AD aged 0-2 years and 12-14 years.
  • Among patients with AD, BMI was significantly higher in those with severe AD in the 9-12 and 12-14 years groups.
  • Mean serum lipid levels were higher in patients with severe AD vs the AD group as a whole.


Agόn-Banzo, et al. Body mass index and serum lipid profile: Association with atopic dermatitis in a pediatric population. [Published online ahead of print September 10, 2019]. Australas J Dermatol. doi: 10.1111/ajd.13154.


In psoriasis, there has been an understanding for some years that a variety of comorbidities occur, including metabolic abnormalities and overweight/obesity. More recently, some data have been published discussing comorbidities in patients with AD. In this small study, patients with severe AD compared to all AD patients had elevated serum lipid levels and in some groups, elevated BMI. Although not addressed in this study, it may be that those with more severe disease were more likely to have been treated with systemic corticoids resulting in weight gain, or perhaps there are lifestyle and behavioral factors occurring. Further study will be needed to determine if better control of AD alone results in improvement in these measures. — Joseph Fowler, Jr., MD, Clinical Professor of Dermatology, University of Louisville, KY