Investigational body wash formulas with lipids were safe and effective in reducing the needs for corticosteroids in children with atopic dermatitis (AD), a new study found. The randomized controlled clinical study was conducted among children aged 4-18 years with mild-to-moderate AD to evaluate the skin health effect of 3 cleansing systems: a mild synthetic bar, an ultra-mild body wash with lipids, and an ultra-mild body wash with lipids and zinc pyrihione. Researchers found:
- Increased Staphylococcus aureus abundance and decreased microbial diversity were observed in AD lesion sites vs health control sites.
- After 4 weeks of treatment, all 3 treatments showed clinically important improvement from baseline.
- 4-week corticosteroid consumption was significantly lower for the 2 body wash groups vs the bar group.
Xu Z, et al. Skin benefits of moisturizing body wash formulas for children with atopic dermatitis: A randomized controlled clinical study in China. [Published online ahead of print September 11, 2019]. Australas J Dermatol. doi: 10.1111/ajd.13153.