Clinical Edge

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Atopic Dermatitis & Sleep Quality in Children

JAMA Pediatr; ePub 2019 Mar 4; Ramirez, et al

Atopic dermatitis (AD) may be associated with impaired sleep quality throughout childhood, therefore clinicians should consider sleep quality among all children with AD, especially those with comorbid asthma or allergic rhinitis and severe disease. This according to a longitudinal cohort study of 13,988 children alive at 1 year and followed up with repeated measures of self-reported AD and sleep through aged 16 years. Among the findings:

  • 35.3% of the study population met the definition of having AD between aged 2 and 16 years.
  • Children with active AD were more likely to report worse sleep quality at all time points than those without AD, with a nearly 50% higher odds of experiencing more sleep-quality disturbances.
  • However, AD was not statistically significantly associated with sleep duration throughout childhood.
  • Children with more severe active disease and with comorbid asthma or allergic rhinitis had worse sleep quality.


Ramirez FD, Chen S, Langan SM, et al. Association of atopic dermatitis with sleep quality in children. [Published online ahead of print March 4, 2019]. JAMA Pediatr. doi:10.1001/jamapediatrics.2019.0025.