Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Eye Problems May Signal Zika Infection

JAMA Pediatr; ePub 2017 Jul 17; Zin, et al

Any infant who may have been exposed to the Zika virus through maternal transmission should have an eye exam, as ophthalmic abnormalities may be the only initial indication that the child has been infected, according to an international team of experts. Their findings include the following:

  • A case series that included 112 infants born to mothers with confirmed Zika infection found 24 had eye problems (21.4%).
  • 10 of these infants did not have microcephaly and 8 didn’t have any central nervous system complications.

Citation:

Zin AA, Tsui R, Rossetto J, et al. Screening criteria for ophthalmic manifestations of congenital Zika virus infection. [Published online ahead of print July 17, 2017]. JAMA Pediatr. doi:10.1001/jamapediatrics.2017.1474.

This Week's Must Reads

Enterovirus in at-risk children associated with later celiac disease, Kahrs CR et al. BMJ. 2019 Feb 13. doi: 10.1136/bmj.l231

Umbilical cord milking tied to severe IVH in very premature neonates, Katheria AC et al. The Pregnancy Meeting, late breaking abstract 1.

Water Fluoridation and Income-Related Dental Caries, JAMA Pediatrics; ePub 2019 Jan 28; Sanders, et al

Trends in Pediatric Hospitalizations, Readmissions, Pediatrics; ePub 2019 Jan 29; Bucholz, et al

High Cost of Home Respiratory Equipment, Supply Use, J Pediatr; ePub 2019 Jan 4; Berry, Goodman, et al

Must Reads in Asthma

PARS Efficacious in Predicting Asthma Development, J Allergy Clin Immunol; ePub 2018 Dec 13; Biagini Myers, et al

Eosinophilic Esophagitis: A Sign of Allergic March, J Allergy Clin Immunol; ePub 2018 Jun 25; Hill, et al

Probiotics May Not Prevent Eczema or Asthma, Pediatrics; ePub 2017 Sep 1; Cabana, et al

Eye Problems May Signal Zika Infection, JAMA Pediatr; ePub 2017 Jul 17; Zin, et al