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Predicting RCC Outcomes After Surgery

Eur Urol; ePub 2018 Feb 2; Leibovich, et al

It appears possible to predict renal cell carcinoma (RCC) progression and death using readily available clinical and pathologic features, researchers concluded after conducting a retrospective cohort review involving >3,600 individuals. Participants had clear cell RCC (ccRCC; n=2,726), papillary RCC (papRCC; n=607), or chromophobe RCC (chrRCC; n=222). Investigators developed models based on clinicopathologic features to predict oncologic outcomes. Among the results:

  • Progression-free survival c-index was 0.83 for ccRCC, 0.77 for papRCC, and 0.78 for chrRCC.
  • Cancer-specific survival c-indexes were 0.86 for ccRCC and 0.83 for papRCC.
  • Due to only 22 deaths from RCC, cancer-specific survival was not assessed for chrRCC.
Citation:

Leibovich B, Lohse C, Cheville J, et al. Predicting oncologic outcomes in renal cell carcinoma after surgery. [Published online ahead of print February 2, 2018]. Eur Urol. doi:10.1016/j.eururo.2018.01.005.

This Week's Must Reads

Predicting RCC Outcomes After Surgery , Eur Urol; ePub 2018 Feb 2; Leibovich, et al

Partial vs Radical Nephrectomy Impact on Survival , Eur Urol Focus; ePub 2018 Feb 2; Marchioni, et al

Robotic Partial Nephrectomy for Large Renal Masses , BJU Int; ePub 2018 Jan 22; Delto, Paulucci, et al

Trends Examined in the Reporting of RCC Subtypes, Hum Pathol; ePub 2018 Jan 12; Gansler, et al

VEGFR Therapy’s Role in Reducing RCC Progression , Curr Med Res Opin; ePub 2018 Feb 1; Tannir, et al

Must Reads in Renal Cell Carcinoma

Predicting RCC Outcomes After Surgery , Eur Urol; ePub 2018 Feb 2; Leibovich, et al

Partial vs Radical Nephrectomy Impact on Survival , Eur Urol Focus; ePub 2018 Feb 2; Marchioni, et al

Robotic Partial Nephrectomy for Large Renal Masses , BJU Int; ePub 2018 Jan 22; Delto, Paulucci, et al

Trends Examined in the Reporting of RCC Subtypes, Hum Pathol; ePub 2018 Jan 12; Gansler, et al

VEGFR Therapy’s Role in Reducing RCC Progression , Curr Med Res Opin; ePub 2018 Feb 1; Tannir, et al