Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Survey indicates opioid prescriptions have decreased

Physicians' progress to reverse the nation's opioid epidemic. American Medical Association.

Key clinical point: Prescriptions for opioids decreased by 22% over the last 5 years and did so in all 50 states.

Major finding: Providers dispensed almost 56 million fewer opioid prescriptions in 2017 than they did in 2013. The total number of prescriptions fell from a total of nearly 252 million in 2013 to 196 million in 2017.

Study details: The number of health care professionals registered for prescription drug monitoring programs more than tripled as well.

Read the article.

This Week's Must Reads

PFS superior with avelumab and axitinib in advanced RCC, Motzer RJ et al. ESMO 2018. Abstract LBA6_PR

Adjuvant axitinib may benefit highest risk RCC patients, Quinn DI et al. Ann Oncol. 2018 Oct 20. doi: 10.1093/annonc/mdy454

High KPNA2 signals poor outcomes for RCC, Kristiansen G et al. Clin Genitourin Cancer. 2018 Oct 22. doi: 10.1016/j.clgc.2018.10.008

RCC patient and disease characteristics differ by race/ethnicity, Batai K et al. Clin Genitourin Cancer. 2018 Oct 26. doi: 10.1016/j.clgc.2018.10.012

Change in tumor burden signals treatment needs in mRCC, Bimbatti D et al. Urol Oncol. 2018 Oct 6. doi: 10.1016/j.urolonc.2018.08.018

Must Reads in Practice Management

Broad opioid legislation advances in Congress, Senate floor debate, Sept. 17, 2018

Early supportive care cuts costs related to curative treatment, Koprowski CD et al. 2018 ASCO Quality Care Symposium, Abstract 142

Employee deductibles outstrip wages, Kaiser Family Foundation, 2018 Employer Health Benefits

The financial burden of metastatic breast cancer, Wheeler SB et al. Quality Care Symposium, Abstract 32