Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Gender disparity found in oncology research funding

Zhou CD et al. BMJ Open. 2018 Apr 30. doi: 10.1136/bmjopen-2017-018625

Key clinical point: Female cancer researchers receive significantly less funding than their male counterparts.

Major finding: Of 4,186 awards, 2,890 grants (69%) were awarded to male primary investigators (PIs), compared with 1,296 grants (31%) for female PIs.

Study details: An analysis of data on public and philanthropic cancer research funding awarded to U.K. institutions between 2000 and 2013.

Disclosures: No disclosures or conflicts of interest were reported.

Citation:

Citation: Zhou CD et al. BMJ Open. 2018 Apr 30. doi: 10.1136/bmjopen-2017-018625

This Week's Must Reads

New model guides treatment decisions in mRCC, Armstrong AJ et al. Ann Oncol. 2018 Sep 10. doi: 10.1093/annonc/mdy406

mRCC: Jaw osteonecrosis increased with denosumab/antiangiogenics, Guillot A et al. Clin Genitourin Cancer. 2018 Sep 6. doi: 10.1016/j.clgc.2018.08.006.

Brazilian study: TKIs effective in clear cell RCC, Velho PI et al. J Glob Onc. 2018 Sep 10. doi: 10.1200/JGO.18.00073.

SBRT safe, effective in oligometastatic RCC, Franzese et al. J Urol. 2018 Sep 1. doi: 10.1016/j.juro.2018.08.049.

CRP levels and RCC prognosis, Nakayama T et al. Clin Genitourin Cancer. 2018 Aug 11. doi: 10.1016/j.clgc.2018.07.027.

Must Reads in Practice Management

Feds move to streamline oversight of gene therapy, Collins FS and Gottlieb S. N Engl J Med. doi: 10.1056/NEJMp1810628

Better access means better survival for rural cancer patients, Unger JM et al. JAMA Network Open. 2018;1(4):e181235. doi: 10.1001/jamanetworkopen.2018.1235

Financial disclosures in oncology studies often incomplete, Wayant C et al. JAMA Oncol. 2018 Aug 30. doi: 10.1001/jamaoncol.2018.3738

Medicare ACO savings still possible without imposing penalties, McWilliams JM et al. N Engl J Med. doi: 10.1056/NEJMsa1803388

Burnout linked to lower quality patient care, Panagioti M et al. JAMA Intern Med. 2018 Sept 4. doi: 10.1001/jamainternmed.2018.3713.