Key clinical point: New software provides real-time aid to colonoscopists for identifying adenomatous polyps.
Major finding: The software was 98% sensitive, 93% specific, and had a negative predictive value of 0.995 for ruling out adenomatous polyps.
Study details: Single-center review of 36,076 images of polyps and normal colonic tissue.
Disclosures: The software development has no commercial funding. Dr. Tripathi had no disclosures. Dr. Karnes is cofounder of, a company that markets colonoscopy software.
Source: Tripathi PV et al. DDW 2018 (Digestive Disease Week, 2018). Presentation 133.
Tripathi PV et al. DDW 2018 (Digestive Disease Week, 2018). Presentation 133.
This Week's Must Reads
Vanderbilt staging best for predicting overall survival in retroperitoneal sarcoma, Huggett B & Cates J. Modern Pathology; 5 Nov. 2018. https://www.nature.com/articles/s41379-018-0166-8
Older patients with ccRCC may respond better to treatment than younger patients, Feulner et al. Urol Oncol. 2018 Nov 23. doi: 10.1016/j.urolonc.2018.11.006.
DSS of ccRCC patients lower with high hTERT, Zanjani LS et al. Pathology. 2018 Nov 19. doi: 10.1016/j.pathol.2018.08.019.
ccRCC with papillary features best classified as a rare morphologic variant of ccRCC, Alaghehbandan R et al. Ann Diagn Pathol. 2018 Nov 22. doi: 10.1016/j.anndiagpath.2018.11.004.
SRS can effectively control brain metastases in patients with RCC, Wardak Z et al. Clin Genitourin Cancer. 2018 Nov 20. doi: 10.1016/j.clgc.2018.11.006.
Must Reads in Gastroenterology
Refractory esophagogastric cancer: Nivolumab plus ipilimumab ups response rate , Janjigian YY et al. J Clin Oncol. 2018 Aug 15. doi: 10.1200/JCO.2017.76.6212.
Study evaluates surveillance intervals after Barrett's esophagus ablation, Cotton CC et al. Gastroenterology. 2018 Apr 12. doi: 10.1053/j.gastro.2018.04.011.
Software boosts accuracy of colonoscopies, Tripathi PV et al. DDW 2018 (Digestive Disease Week, 2018). Presentation 133.
Colorectal cancer costs twice as much in US as Canada, Yezefski et al. ASCO 2018 Abstract LBA3579.
Fiber Intake and Survival After CRC Diagnosis, JAMA Oncol; ePub 2017 Nov 2; Song, Wu, et al