Negative life events appear to play a role in risk of breast cancer, according to a case-control study involving >860 individuals. Meanwhile, positive events may attenuate negative event effects. Participants included patients with breast cancer (n=664) and population-based controls (n=203). They completed a risk factor questionnaire that included queries about life events. Among the results:
- Negative life events were linked with increased breast cancer risk.
- Patients with ≥4 negative events had a nearly 3-fold increased risk of breast cancer.
- Having a prior illness increased breast cancer risk by >3-fold.
- Having an abortion was linked with a 45% decreased risk of breast cancer.
- While positive life events did not have a significant impact on breast cancer risk, they appeared to buffer the adverse impact of negative events.
Fischer A, Ziogas A, Anton-Culver H. Negative valence life events promote breast cancer development. [Published online ahead of print November 1, 2017]. Clin Breast Cancer. doi:10.1016/j.clbc.2017.10.017.
This Week's Must Reads
Does Integrated Delivery Treatment Impact Cost? , J Oncol Pract; ePub 2018 Feb 13; Kaye, Min, et al
Anticancer Agent Dose Rounding Cost Impact Assessed, J Oncol Pract; ePub 2018 Feb 5; Fahrenbruch, et al
Employment in Patients with Early-Stage BC Studied , Cancer; ePub 2018 Feb 13; Ekenga, Pérez, et al
Program’s Impact on CRC Screening in Uninsured , Cancer; ePub 2018 Feb 7; Eberth, Thibault, et al
Charting the Landscape of Oncology Pathway Vendors , J Oncol Pract; ePub 2018 Feb 7; Daly, Zon, et al
Must Reads in Breast Cancer
FDA Approves Lynparza for Certain Types of BC, FDA news release; 2018 Jan 12
Stereotactic Radiotherapy System Approved For BC, FDA news release; 2017 Dec 22
Perjeta Approved for Certain Type of Early BC, Genentech news release; 2017 Dec 20
Do Women with BC Use Their Pain Meds Correctly?, J Pain Symptom Manage; ePub 2017 Dec 5; Stephenson, et al
Immediate Breast Reconstruction Likelihood Studied, Clin Breast Cancer; ePub 2017 Dec 6; Reddy, et al