Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

This Week's Must Reads

New MOC pathway developed by ABIM, ASCO, Alternative to focus on oncology expertise

Survey indicates opioid prescriptions have decreased , Physicians' progress to reverse the nation's opioid epidemic. American Medical Association.

Oncologists sue over Medicare drug pay cut, Community Oncology Alliance v. Office of Management and Budget et al. ​

Gender disparity found in oncology research funding, Zhou CD et al. BMJ Open. 2018 Apr 30. doi: 10.1136/bmjopen-2017-018625

Trump administration rejects ACA lawsuit, Texas v. The United States centers on the individual mandate

Clinical Guidelines

ASCO Guideline on Alcohol Consumption and Cancer, J Clin Oncol; 2018 Jan; LoConte, Brewster, et al

ASCO Updates Guideline on Role of BMAs in BC, J Clin Oncol; ePub 2017 Oct 16; Van Poznak, et al

Read more in Clinical Guidelines

FDA Actions

Nivolumab plus ipilimumab approved for advanced RCC, FDA approves nivolumab plus ipilimumab combination for intermediate or poor-risk advanced renal cell carcinoma https://www.fda.gov/drugs/informationondrugs/approveddrugs/ucm604685.htm

FDA Approves Lynparza for Certain Types of BC, FDA news release; 2018 Jan 12

Read more in FDA Actions

Gastroenterology

Colorectal cancer costs twice as much in US as Canada, Yezefski et al. ASCO 2018 Abstract LBA3579.

Fiber Intake and Survival After CRC Diagnosis, JAMA Oncol; ePub 2017 Nov 2; Song, Wu, et al

Read more in Gastroenterology

Melanoma

FDA Approves First Treatment for Rare Skin Cancer, FDA news release; 2017 Mar 23

High-Dose Interferon vs Observation for Melanoma , J Clin Oncol; ePub 2017 Jan 30; Agarwala, et al

Read more in Melanoma

Lung Cancer

Atezolizumab boosts outcomes in squamous NSCLC, Jotte et al. ASCO 2018 Abstract LBA9000.

CT scans underused for lung cancer screens, Pham DC et al. ASCO 2018. Abstract 6504.

Read more in Lung Cancer

Patient & Survivor Care

Head and neck cancer therapy toxicities greater in women, Cristina V et al. JAMA Oncol. 2018 May 24. doi: 10.1001/jamaoncol.2018.1080.

Colorectal cancer costs twice as much in US as Canada, Yezefski et al. ASCO 2018 Abstract LBA3579.

Read more in Patient & Survivor Care

Practice Management

New MOC pathway developed by ABIM, ASCO, Alternative to focus on oncology expertise

Survey indicates opioid prescriptions have decreased , Physicians' progress to reverse the nation's opioid epidemic. American Medical Association.

Read more in Practice Management

Head & Neck Cancers

Head and neck cancer therapy toxicities greater in women, Cristina V et al. JAMA Oncol. 2018 May 24. doi: 10.1001/jamaoncol.2018.1080.

CYCORE reduces radiotherapy side effects in head and neck cancers, Peterson et al. ASCO 2018, Abstract 6063

Read more in Head & Neck Cancers

Preventive Care

Predicting Acute Kidney Injury Risk from Cisplatin , J Clin Oncol; ePub 2018 Jan 10; Motwani, et al

ASCO Guideline on Alcohol Consumption and Cancer, J Clin Oncol; 2018 Jan; LoConte, Brewster, et al

Read more in Preventive Care

Breast Cancer

Brain met outcomes similar for NSCLC, breast cancer patients, Cagney DN et al. JAMA Oncol. 2018 May 17. doi: 10.1001/jamaoncol.2018.0813.

Read more in Breast Cancer

Genitourinary Cancer

Access to care linked to better outcomes in black men with prostate cancer, Halabi et al, George et al. ASCO 2018 (annual meeting of the American Society of Clinical Oncology) Abstracts LBA5005 and LBA5009.

Statins may affect prostate cancer microenvironment, Allott E et al. AUA 2018 (annual meeting of the American Urological Association), Abstract MP21-01.

Read more in Genitourinary Cancer