Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Depression Among Women of Childbearing Age

Obstet Gynecol; ePub 2018 Mar 8; Guo, et al

Approximately 5% of US women of childbearing age have symptoms of major depression, with nearly one-third of women with severe symptoms reporting antidepressant use. This according to a cross-sectional study of 3,705 nonpregnant women of childbearing age from the National Health and Nutrition Examination Surveys 2007-2014. The primary outcome is the prevalence of major depression, and secondary outcomes are the prevalence of minor depression, rates of antidepressant use, and predictors of major and minor depression. Researchers found:

  • The overall prevalence of major and minor depression was 4.8% and 4.3%, respectively.
  • The prevalence of antidepressant use among women with major depression and minor depression were 32.4% and 20.0%, respectively.
  • Factors most strongly associated with major depression were government insurance and hypertension; for minor depression, education less than high school or high school education.


Guo N, Robakis T, Miller C, Butwick A. Prevalence of depression among women of reproductive age in the United States. [Published online ahead of print March 8, 2018]. Obstet Gynecol. doi:10.1097/AOG.0000000000002535.

This Week's Must Reads

Low Dose Aspirin and Spontaneous Preterm Birth, Am J Obstet Gynecol; ePub 2018 Jun 15; Andrikopoulou, et al

New Persistent Opioid Use After Hysterectomy, Am J Obstet Gynecol; ePub 2018 Jun 18; Swenson, et al

Salpingectomy at Time of Cesarean Delivery, Contraception; ePub 2018 Jun 20; Lehn, et al

Cardiac Autonomic Function in Midlife Women, Menopause; ePub 2018 Jun 18; Fu, et al

ACOG Recommendations for Maternal Immunization, Obstet Gynecol; ePub 2018 Jun; Ault, Riley, et al

Must Reads in Reproductive Endocrinology

Treatment Update for Polycystic Ovary Syndrome, Obstet Gynecol; ePub 2018 Jun; Legro, et al

Fertility Awareness Based Contraceptive Methods, Contraception; ePub 2018 Apr 25; Polis, et al

Depression Among Women of Childbearing Age, Obstet Gynecol; ePub 2018 Mar 8; Guo, et al

Marijuana Use and Time to Pregnancy, Fertil Steril; ePub 2018 Mar 16; Kasman, et al

Cancer Tx and Infertility Risk in Women with PCOS, Fertil Steril; ePub 2018 Feb 7; Shandley, et al