Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Antihypertensive Med Use to Treat Preeclampsia

Obstet Gynecol; ePub 2018 Feb 5; Cleary, et al

For women with mild, superimposed, and severe preeclampsia, the use of multiple antihypertensive agents during delivery hospitalization increased and was associated with decreased risk of maternal stroke, a recent study found. The retrospective cohort study evaluated antihypertensive drugs dispensed during delivery hospitalizations complicated by preeclampsia from 2006 to the first quarter of 2015. Among the details:

  • 236,454 patients with preeclampsia were included in the analysis: 126,595 women with mild, 31,628 with superimposed, and 81,231 with severe preeclampsia.
  • Overall, 105,409 women received a hypertensive agent.
  • The proportion of patients with preeclampsia receiving any antihypertensive medication rose from 37.8% in 2006 to 49.4% in 2015.
  • Rates of antihypertensive administration for severe preeclampsia varied significantly by hospital.
  • For severe preeclampsia, the risk for stroke decreased from 13.5 per 10,000 deliveries in 2006-2008, to 9.7 in 2009-2011, to 6.0 in 2012-2014.

Citation:

Cleary KL, Siddiq Z, Ananth CV, et al. Use of antihypertensive medications during delivery hospitalization complicated by preeclampsia. [Published online ahead of print February 5, 2018]. Obstet Gynecol. doi:10.1097/AOG.0000000000002479.

This Week's Must Reads

Low Dose Aspirin and Spontaneous Preterm Birth, Am J Obstet Gynecol; ePub 2018 Jun 15; Andrikopoulou, et al

New Persistent Opioid Use After Hysterectomy, Am J Obstet Gynecol; ePub 2018 Jun 18; Swenson, et al

Salpingectomy at Time of Cesarean Delivery, Contraception; ePub 2018 Jun 20; Lehn, et al

Cardiac Autonomic Function in Midlife Women, Menopause; ePub 2018 Jun 18; Fu, et al

ACOG Recommendations for Maternal Immunization, Obstet Gynecol; ePub 2018 Jun; Ault, Riley, et al

Must Reads in Obstetrics

Low Dose Aspirin and Spontaneous Preterm Birth, Am J Obstet Gynecol; ePub 2018 Jun 15; Andrikopoulou, et al

Preconception Vitamin D Key After Pregnancy Loss, Lancet Diabetes Endocrinol; ePub 2018 May 30; Mumford, et al

PA & Risk of Preterm Birth in African American Women, Women’s Health Issues; ePub 2018 May 7; Straughen, et al

ACOG On Optimizing Postpartum Care, Obstet Gynecol; ePub 2018 May; Stuebe, et al

Cesarean Delivery Rates in the US , Am J Obstet Gynecol; ePub 2018 Apr 12; Hehir, et al