Vascular dysfunction across the stages of menopause is associated with greater frequency and severity of menopausal symptoms and lower quality of life, but not depression, according to a recent study. Researchers measured arterial stiffness, endothelial function, menopausal symptoms, depression, and quality of life (QOL) in 138 premenopausal women. They found:
- Menopausal symptoms, depression, and QOL worsened across menopause stages, particularly in late perimenopausal women.
- Vasosomatic symptom frequency and general somatic symptom frequency and severity were inversely correlated with carotid artery compliance and FMD.
- Only correlations with general somatic symptoms were significant after adjusting for multiple comparisons.
- Total QOL was positively correlated with carotid artery compliance.
Hildreth KL, Ozemek C, Kohrt WM, Blatchford P, Moreau KL. Vascular dysfunction across the stages of the menopausal transition is associated with menopausal symptoms and quality of life. [Published online ahead of print April 9, 2018]. Menopause. doi:10.1097/GME.0000000000001112.
This Week's Must Reads
Low-Dose Aspirin Use During Pregnancy, Obstet Gynecol; ePub 2018 Jul; ACOG, SMFM
Postpartum Pain & Fatigue Management , Obstet Gynecol; ePub 2018 Jul; ACOG
Vaginal Preparation Before Cesarean Section, Cochrane Library; ePub 2018 Jul 17; Haas, et al
Maternal Outcomes by Race in Women Aged ≥40 Years, Obstet Gynecol; ePub 2018 Jul 10; Booker, et al
Orilissa Approved for Pain Management of Endometriosis, AbbVie news release; 2018 July 24
Must Reads in Menopause
Cardiac Autonomic Function in Midlife Women, Menopause; ePub 2018 Jun 18; Fu, et al
Vasomotor Symptoms in Older Women, Menopause; ePub 2018 May 7; David, et al
Estrogen-alone Therapy & Invasive Breast Cancer, Menopause; ePub 2018 May 7; Shufelt, et al
Vascular Dysfunction During Menopausal Transition, Menopause; ePub 2018 Apr 9; Hildreth, et al
Menopausal HT & Hyperkyphosis Prevention , Menopause; ePub 2018 Feb 16; Woods, et al