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Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Do Vasomotor Symptoms Elevate Diabetes Risk?

Menopause; ePub 2017 Dec 4; Gray, Katon, et al

Vasomotor symptoms (VMS) are associated with elevated diabetes risk, predominantly for women with night sweats and postmenopausal symptoms, a recent study found. Associations of incident diabetes with VMS characteristics were examined among 150,007 postmenopausal Women’s Health Initiative participants from 1993 to 2014, with mean duration of follow-up at 13.1 years. Researchers found:

  • VMS prevalence was 33.0%.
  • Reporting any VMS was associated with 18% increased diabetes risk, which increased with severity (mild: HR 1.13; moderate: HR 1.29; severe: HR 1.48) and duration (4% per 5 years), independent of obesity.
  • Diabetes risk was more pronounced for women reporting any night sweats than only hot flashes and was restricted to late VMS.


Gray KE, Katon JG, LeBlanc ES, et al. Vasomotor symptom characteristics: Are they risk factors for incident diabetes? [Published online ahead of print December 4, 2017]. Menopause. doi:10.1097/GME.0000000000001033.

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