Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Cardiac Autonomic Function in Midlife Women

Menopause; ePub 2018 Jun 18; Fu, et al

Midlife women with increased anxiety and depressive symptoms may have an unfavorable cardiac autonomic profile with potential implications for their overall cardiovascular (CV) risk, a recent study suggests. Anxiety and depressive symptoms were evaluated by validated self-administered questionnaires among perimenopausal and postmenopausal women in a randomized trial of slow-paced respiration for hot flashes. Pre-ejection period (PEP) and respiratory sinus arrhythmia (RSA), were measured at baseline and 12 weeks using impedance cardiography and electrocardiography. Researchers found:

  • Among 121 participants, greater state anxiety was associated with shorter PEP, reflecting higher sympathetic activity.
  • Greater trait anxiety and cognitive anxiety were associated with lower RSA, reflecting decreased parasympathetic activity.
  • Greater depressive symptoms were associated with lower RSA.

Citation:

Fu P, Gibson CJ, Mendes WB, Schembri M, Huang AJ. Anxiety, depressive symptoms, and cardiac autonomic function in perimenopausal and postmenopausal women with hot flashes: a brief report. [Published online ahead of print June 18, 2018]. Menopause. doi:10.1097/GME.0000000000001153.

This Week's Must Reads

Low Dose Aspirin and Spontaneous Preterm Birth, Am J Obstet Gynecol; ePub 2018 Jun 15; Andrikopoulou, et al

New Persistent Opioid Use After Hysterectomy, Am J Obstet Gynecol; ePub 2018 Jun 18; Swenson, et al

Salpingectomy at Time of Cesarean Delivery, Contraception; ePub 2018 Jun 20; Lehn, et al

Cardiac Autonomic Function in Midlife Women, Menopause; ePub 2018 Jun 18; Fu, et al

ACOG Recommendations for Maternal Immunization, Obstet Gynecol; ePub 2018 Jun; Ault, Riley, et al

Must Reads in Menopause

Cardiac Autonomic Function in Midlife Women, Menopause; ePub 2018 Jun 18; Fu, et al

Vasomotor Symptoms in Older Women, Menopause; ePub 2018 May 7; David, et al

Estrogen-alone Therapy & Invasive Breast Cancer, Menopause; ePub 2018 May 7; Shufelt, et al

Vascular Dysfunction During Menopausal Transition, Menopause; ePub 2018 Apr 9; Hildreth, et al

Menopausal HT & Hyperkyphosis Prevention , Menopause; ePub 2018 Feb 16; Woods, et al