The experience of infertility at any point in a women’s reproductive lifecycle may be associated with later-life cardiovascular (CV) health, a recent study found. In a cross-sectional analysis among US women from the National Health and Nutrition Examination Survey (2013-2014), researchers examined the association of self-reported infertility and metabolic syndrome and CV events, including congestive heart failure, coronary heart disease (CHD), heart attack, or stroke. Among the details:
- 744 US women aged 20‒59 years participated in the study.
- 15.7% reported ever experiencing infertility, 27.6% met the definition of metabolic syndrome, and 2.84% reported ever having a CV event.
- Compared to women who had never experienced infertility, women who reported infertility had a 1.79 higher odds of reporting symptoms of metabolic syndrome and 1.83 times higher odds of having experienced a CV event.
- Women with self-reported infertility also had 71% higher odds of reporting a CV event after controlling for metabolic syndrome.
Gleason JL, Shenassa ED, Thoma ME. Self-reported infertility, metabolic dysfunction, and cardiovascular events: A cross-sectional analysis among U.S. women. [Published online ahead of print November 17, 2018]. Fertil Steril. doi:10.1016/j.fertnstert.2018.10.009.
This Week's Must Reads
Must Reads in Reproductive Endocrinology
Fertility Treatment and Breastfeeding Outcomes , Am J Obstet Gynecol; ePub 2018 Dec 1; Barrera, et al
Infertility, Metabolic Dysfunction & CV Events, Fertil Steril; ePub 2018 Nov 17; Gleason, et al
Severe Maternal Morbidity by Maternal Fertility Status, Am J Obstet Gynecol; ePub 2018 Oct 12; Luke, et al
Vitamin D Levels and Ovarian Reserve, Fertil Steril; 2018 Sep; Shapiro, Darmon, et al
Leukemia risk after maternal contraception use, Hargreave M et al. Lancet Oncol. 2018 Sep 6. doi: 10.1016/S1470-2045(18)30479-0