Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Opioid Prescribing After Surgery for Pelvic Organ Prolapse

Female Pelvic Med Reconstr Surg; ePub 2018 Sep 22; Leach, et al

Among women undergoing surgical treatment for pelvic organ prolapse, pain scores, opioid prescription amounts at discharge, and refills varied by patient age and surgical approach but were unaffected by associated procedures, a recent study found. The cohort was organized by surgical approach (open, endoscopic, vaginal), number of concomitant procedures, and patient age stratified by decade. These factors were then matched to postoperative pain scores, amount of opioid prescribed at discharge, and number of subsequent opioid refills. Researchers found:

  • 1,830 patients underwent surgical treatment of pelvic organ prolapse and met study criteria.
  • A significant decrease in pain scores, mean oral morphine equivalents prescribed, and opioid refill rates was seen with increasing patient age by decade regardless of surgical approach.
  • Pain scores were significantly different only between patients undergoing vaginal surgery with no concomitant procedures vs ≥1 concomitant procedures.
  • Pain scores were directly correlated to the amount of opioid prescribed.


Leach AD, Habermann EB, Glasgow AE, Occhino JA. Postoperative opioid prescribing following gynecologic surgery for pelvic organ prolapse. [Published online ahead of print September 22, 2018]. Female Pelvic Med Reconstr Surg. doi:10.1097/SPV.0000000000000628.

Must Reads in Pelvic Floor Dysfunction

Apical Suspension at the Time of Vaginal Hysterectomy, Female Pelvic Med Reconstr Surg; ePub 2019 Feb 21; Sheyn, et al

Activity After Gynecologic & Pelvic Reconstructive Surgery, Female Pelvic Med Reconstr Surg; ePub 2019 Jan 30; Winkelman, et al

Overactive Bladder Symptoms After POP Surgery, Female Pelvic Med Reconstr Surg; ePub 2019 Jan 23; Johnson, et al

POP and UI Knowledge in Bariatric Surgery, Female Pelvic Med Reconstr Surg; ePub 2019 Jan 11; Paka, et al