Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Universal HCV Testing in Prenatal Care

Obstet Gynecol; ePub 2019 Jan 8; Tasillo, et al

Universal prenatal hepatitis C virus screening (HCV) improves health outcomes in women with HCV infection, improves identification of HCV exposure in neonates born at risk, and is cost-effective, a new study found. Researchers simulated the lifetimes of 250 million pregnant women matched at baseline with the US childbearing population on age, injection drug use behaviors, and HCV infection status. Outcomes included HCV diagnosis, treatment and cure, lifetime health care costs, quality-adjusted life years (QALY), and incremental cost-effectiveness ratios comparing universal prenatal HCV screening to current practice. They found:

  • Pregnant women with HCV infection lived 1.21 years longer and had 16% lower HCV-attributable mortality with universal prenatal HCV screening.
  • Universal HCV screening had an incremental cost-effectiveness ratio of $41,000 per QALY gained vs current practice.
  • Universal prenatal HCV screening increased identification of neonates exposed to HCV at birth from 44 to 92%.

Citation:

Tasillo A, Eftekhari Yazdi E, Nolen S, et al. Short-term effects and long-term cost-effectiveness of universal hepatitis C testing in prenatal care. [Published online ahead of print January 8, 2019]. Obstet Gynecol. doi:10.1097/AOG.0000000000003062.

This Week's Must Reads

Universal HCV Testing in Prenatal Care, Obstet Gynecol; ePub 2019 Jan 8; Tasillo, et al

Is GDM Associated with Neonatal Respiratory Morbidity?, Obstet Gynecol; ePub 2019 Jan 8; Werner, et al

POP and UI Knowledge in Bariatric Surgery, Female Pelvic Med Reconstr Surg; ePub 2019 Jan 11; Paka, et al

Maternal Factors in Cervical Cancer Prevention, Womens Health Issues; ePub 2019 Jan 10; Charlton, et al

ACOG: Chronic Hypertension in Pregnancy, Obstet Gynecol; ePub 2019 Jan; Vidaeff, et al

Must Reads in Obstetrics

Universal HCV Testing in Prenatal Care, Obstet Gynecol; ePub 2019 Jan 8; Tasillo, et al

Is GDM Associated with Neonatal Respiratory Morbidity?, Obstet Gynecol; ePub 2019 Jan 8; Werner, et al

ACOG: Chronic Hypertension in Pregnancy, Obstet Gynecol; ePub 2019 Jan; Vidaeff, et al

Inflammatory Cytokines & Perinatal Depression, Am J Obstet Gynecol; ePub 2018 Dec 14; Miller, et al

ACOG Guidelines: Pregestational Diabetes Mellitus, Obstet Gynecol; ePub 2018 Dec; ACOG, et al