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Small study links preterm birth, maternal preconception phthalate exposure

Key clinical point: Maternal phthalate exposure prior to conception may be associated with shorter gestation.

Major finding: Maternal preconception phthalate concentrations were associated with a 50% increased risk of preterm birth (P = .01).

Study details: Prospective cohort study of 419 mothers and 229 fathers participating in the Environment and Reproductive Health (EARTH) Study; 34 babies were born preterm.

Disclosures: The National Institute of Environmental Health Science funded the study. Two study coauthors received grants from the NIEHS, one coauthor received grants from the National Institutes of Health, and one received a grant from the Canadian Institutes of Health Research. No other disclosures were reported.