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Perinatal Outcomes in Women with Chronic Hypertension

Obstet Gynecol; ePub 2018 Apr 6; Youngstrom, et al

Pregnant women with chronic hypertension but normal blood pressures before 20 weeks of gestation are at an increased risk of adverse perinatal outcomes compared with women without chronic hypertension, a recent study found. The retrospective cohort included singletons with a history of chronic hypertension from 2000 to 2014. Researchers found:

  • Of 830 women with chronic hypertension and BPs <140/90 mm Hg before 20 weeks of gestation, 212 (26%) were not taking antihypertensive medication and 618 (74%) were. These groups were compared with 476 women without chronic hypertension.
  • Women with hypertension were more likely to be older and have baseline renal disease and diabetes compared with women in the no hypertension group.
  • The perinatal composite was more common in both hypertensive groups: no antihypertensive medication (9.9%) and antihypertensive medication (14.6%) compared with women in the control group (2.9%).
  • The risk of early preterm birth, small for gestational age, and preeclampsia was not significantly increased in women with chronic hypertension and no antihypertensive medications vs women without chronic hypertension.
Citation:

Youngstrom M, Tita A, Grant J, Szychowski JM, Harper LM. Perinatal outcomes in women with a history of chronic hypertension but normal blood pressures before 20 weeks of gestation. [Published online ahead of print April 6, 2018]. Obstet Gynecol. doi:10.1097/AOG.0000000000002574.

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