Clinical Edge

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Local Transmission of Zika Virus in the US

MMWR; ePub 2016 Sep 13; Walker, Lindsey, et al

Although most cases of Zika virus disease in the US are travel-associated, local transmission has been reported and health care providers should continue to educate patients, especially pregnant women, about the importance of avoiding infection with Zika virus. This according to a report of Zika virus disease cases in the 50 states and the District of Columbia from January 1 to July 31, 2016. Among the findings and recommendations:

• 2,382 confirmed or probable cases of Zika virus disease with symptom onset during January 1 to July 31, 2016 were reported to ArboNET, as of September 3, 2016.

• 99% of cases reported were travel-associated.

• However, locally-acquired cases include 26 mosquito-borne disease cases, 1 laboratory-acquired infection, and 1 patient with unknown transmission mode.

• 65 (3%) patients were hospitalized, and 1 died.

• All pregnant women should be assessed for possible Zika virus exposure at each prenatal visit.

• Zika virus disease should be considered in patients with compatible clinical signs or symptoms who traveled to or reside in areas with ongoing Zika virus transmission or who had unprotected sex with someone who traveled to those areas.


Walker WL, Lindsey NP, Lehman JA, et al. Zika virus disease cases—50 States and the District of Columbia, January 1 - July 31, 2016. [Published online ahead of print September 13, 2016]. MMWR Morb Mortal Wkly Rep. doi:10.15585/mmwr.mm6536e5.