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Is GDM Associated with Neonatal Respiratory Morbidity?

Obstet Gynecol; ePub 2019 Jan 8; Werner, et al

Maternal gestational diabetes mellitus (GDM) is not associated with increased neonatal respiratory morbidity among women at high risk for late preterm birth, a recent study found. The secondary analysis of a randomized placebo-controlled trial in which women with singleton pregnancies at high risk for delivery between 34 0/7 and 36 5/7 weeks of gestation were allocated to betamethasone or placebo. The primary outcome was a composite outcome of neonatal respiratory morbidity in the first 72 hours of life. Among the details:

  • Of 2,831 women enrolled in the trial, 306 (10.8%) had GDM.
  • Women with GDM were significantly older and were more likely to be parous and to have hypertensive disorders of pregnancy vs those without GDM.
  • Neonates born to women with GDM were no more likely to meet the primary outcomes than those born to women without GDM, even after adjustments.

Citation:

Werner EF, Romano ME, Rouse DJ, et al. Association of gestational diabetes mellitus with neonatal respiratory morbidity. [Published online ahead of print January 8, 2019]. Obstet Gynecol. doi:10.1097/AOG.0000000000003053.