Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Conceiving After Pregnancy Loss

How long should couples wait?

Couples who began trying to achieve pregnancy within 3 months of their last pregnancy loss had just as fast, if not faster, time to pregnancy leading to a live birth, with no risk of pregnancy complications, as those who waited until after 3 months to start trying. This according to a secondary analysis of 1,083 women aged 18 to 40 years with 1 or 2 prior early losses and whose last pregnancy outcome was a nonectopic or nonmolar loss. Researchers found:

• Couples with a 0 to 3 month interval (n=765) compared with a >3 month interval (n=233) were more likely to achieve live birth (53.2% vs 36.1%) with a significantly shorter time to pregnancy leading to live birth (OR=1.71).

• Additionally, adjusting for low-dose aspirin treatment did not appreciably alter estimates.

Citation: Schliep KC, Mitchell EM, Mumford SL, et al. Trying to conceive after an early pregnancy loss. [Published online ahead of print January 7, 2016]. Obstet Gynecol. doi: 10.1097/AOG.0000000000001159.