Key clinical point: High maternal lead exposure may increase risk of childhood obesity, but this could be mitigated by maternal folate levels.
Major finding: Children of mothers with 5 mcg/dL or more blood lead levels had 65% increased risk of overweight/obesity. Among children whose mothers were overweight/obese and had high blood lead levels, however, high folate levels appeared protective against obesity.
Study details: The findings are based on a prospective U.S. urban, low-income cohort study from 2002 to 2013 that enrolled 1,442 mother-child pairs.
Disclosures: The research was funded by the National Institutes of Health and the U.S. Department of Health and Human Services. The study authors had no industry financial disclosures.