Clinical Edge

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Vasomotor Symptoms and Hemostatic Parameter Levels

Menopause; ePub 2016 Dec 5; Harrington, et al

Vasomotor symptoms (VMS) presence or severity was not associated with levels of hemostatic parameters, a recent study found. The cross-sectional analysis included 2,148 postmenopausal women with measures of VMS presence and severity reported in the 4 weeks before Women’s Health Initiative (WHI) baseline, and not using warfarin or hormone therapy. Researchers found:

  • Women were aged 67 years on average and 33% reported VMS presence at baseline.
  • VMS presence may be associated with a -0.34 adjusted difference in normalized activated protein C sensitivity ratio compared with no VMS, but this association was not significant.
  • VMS presence or severity was not significantly associated with the other hemostatic parameters.


Harrington LB, Blondon M, Cushman M, et al. The cross-sectional association between vasomotor symptoms and hemostatic parameter levels in postmenopausal women. [Published online ahead of print December 5, 2016]. Menopause. doi:10.1097/GME.0000000000000777.