Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Tobacco Smoke & Incident Fibroids Risk

Fertil Steril; ePub 2016 Jul 18; Wong, Chang, et al

There was an increased risk of late diagnosis incident fibroids in midlife in women undergoing menopausal transition and exposed to environmental tobacco smoke (ETS). This according the 13-year prospective Study of Women’s Health across the Nation (SWAN) that included a multiracial/ethnic cohort of 2,575 women aged 42 to 52 years at baseline and undergoing menopausal transition. Researchers found:

• Women exposed to ETS ≥1 person-hour per week had 1.28 times the adjusted odds of incident fibroids in the ensuing year vs those that were unexposed.

• Odds were elevated in never smokers (adjusted OR, 1.34) and former smokers (aOR, 2.57).

Citation:

Wong JY, Chang PY, Gold EB, Johnson WO, Lee JS. Environmental tobacco smoke and risk of late-diagnosis incident fibroids in the Study of Women’s Health across the Nation (SWAN). [Published online ahead of print July 18, 2016]. Fertil Steril. doi:10.1016/j.fertnstert.2016.06.025.