Clinical Edge

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Obstructive Sleep Apnea in Women

Is nocturnal enuresis a factor?

Obstructive sleep apnea (OSA) risk factors were associated with nocturnal enuresis in postmenopausal women in a cohort study of 2,789 women aged 50 to 79 years. According to the study, mechanisms relating nocturnal enuresis to OSA may include apnea-associated changes in intrathoracic pressure, leading to increased urine output. Researchers also found:

• 1.7% reported having nocturnal enuresis.

• Obesity (OR=2.29), snoring (OR=2.01), poor sleep quality (OR=1.70), sleep fragmentation (OR=2.44), daytime sleepiness (OR=1.50), and hypertension (OR=1.13) were also associated with nocturnal enuresis.

• Each additional OSA risk factor in a predefined OSA score significantly increased the odds of having nocturnal enuresis in a dose-response fashion compared with no risk factors.

Citation: Koo P, McCool DF, Hale L, Stone K, Eaton CB. Association of obstructive sleep apnea risk factors with nocturnal enuresis in postmenopausal women. Menopause. [Published online ahead of print August 31, 2015]. doi: 10.1097/GME.0000000000000517.