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Family history of MI may increase CVD mortality after bilateral salpingo-oophorectomy

Key clinical point: Family history of premature MI and bilateral salpingo-oophorectomy combo is linked to higher cardiovascular disease mortality and heart disease mortality.

Major finding: The multivariable adjusted hazard ratios were 2.55 for cardiovascular disease mortality and 3.51 for heart disease mortality in women with both first-degree family history of premature MI and bilateral salpingo-oophorectomy, compared with women who had neither.

Study details: An analysis of 2,763 postmenopausal women aged 40 years and older from the National Health and Nutrition Examination Survey III.

Disclosures: The authors reported no funding or conflicts of interest.


Appiah D et al. Menopause. 2020 Feb. doi: 10.1097/GME.0000000000001522.