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Diet & Fracture Risk in Postmenopausal Women

JAMA Intern Med; ePub 2016 Mar 28; Haring, et al

A healthy dietary pattern, including a higher adherence to a Mediterranean diet, may play a role in maintaining bone health in postmenopausal women and lower the risk of fractures. This according to results from the Women’s Health Initiative (WHI) and 90,014 participants (mean age 63.6 years). The WHI food frequency questionnaire was used to derive nutrient and food intake at baseline and diet quality and adherence were assessed by scores on the alternate Mediterranean diet (aMED). Researchers found:

• During a median follow-up of 15.9 years, there were 2,121 cases of hip fractures and 28,718 cases of total fractures.

• Women scoring in the highest quintile (Q5) of the aMED index had a lower risk for hip fractures (HR=0.80), with an absolute risk reduction of 0.29% and a number needed to treat of 342.

• No association between the aMED score and total fractures was observed (Q5 HR=1.01).

• Higher HEI-2010 or DASH scores tended to be inversely related to hip fracture risk, but the results were nonsignificant (Q5 HR=0.87).

Citation: Haring B, Crandall CJ, Wu C, et al. Dietary patterns and fractures in postmenopausal women: Results from the Women’s Health Initiative. [Published online ahead of print March 28, 2016]. JAMA Intern Med. doi:10.1001/jamainternmed.2016.0482.