Midlife women with increased anxiety and depressive symptoms may have an unfavorable cardiac autonomic profile with potential implications for their overall cardiovascular (CV) risk, a recent study suggests. Anxiety and depressive symptoms were evaluated by validated self-administered questionnaires among perimenopausal and postmenopausal women in a randomized trial of slow-paced respiration for hot flashes. Pre-ejection period (PEP) and respiratory sinus arrhythmia (RSA), were measured at baseline and 12 weeks using impedance cardiography and electrocardiography. Researchers found:
- Among 121 participants, greater state anxiety was associated with shorter PEP, reflecting higher sympathetic activity.
- Greater trait anxiety and cognitive anxiety were associated with lower RSA, reflecting decreased parasympathetic activity.
- Greater depressive symptoms were associated with lower RSA.
Fu P, Gibson CJ, Mendes WB, Schembri M, Huang AJ. Anxiety, depressive symptoms, and cardiac autonomic function in perimenopausal and postmenopausal women with hot flashes: a brief report. [Published online ahead of print June 18, 2018]. Menopause. doi:10.1097/GME.0000000000001153.
This Week's Must Reads
Prophylactic Antibiotic Use in Labor & Delivery, Obstet Gynecol; 2018 Sep; Coleman, et al
USPSTF on Screening for Cervical Cancer, JAMA; 2018 Aug 21; US Preventive Services Task Force
Prevention of Obstetric Lacerations at Vaginal Delivery, Obstet Gynecol; 2018 Sep; Cichowski, et al
Effect of Menstrual Bleeding on IUD Discontinuation, Am J Obstet Gynecol; ePub 2018 Aug 28; Hobby, et al
Leukemia risk after maternal contraception use, Hargreave M et al. Lancet Oncol. 2018 Sep 6. doi: 10.1016/S1470-2045(18)30479-0
Must Reads in Menopause
Cardiac Autonomic Function in Midlife Women, Menopause; ePub 2018 Jun 18; Fu, et al
Vasomotor Symptoms in Older Women, Menopause; ePub 2018 May 7; David, et al
Estrogen-alone Therapy & Invasive Breast Cancer, Menopause; ePub 2018 May 7; Shufelt, et al
Vascular Dysfunction During Menopausal Transition, Menopause; ePub 2018 Apr 9; Hildreth, et al
Menopausal HT & Hyperkyphosis Prevention , Menopause; ePub 2018 Feb 16; Woods, et al