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Can Weight Loss Help Prevent VMS?

Menopause; ePub 2016 Oct 3; Gold, Crawford, et al

Concurrent body mass index (BMI) and waist circumference were positively related to incident vasomotor symptoms (VMS) in early menopause, but negatively related in late menopause, suggesting that maintaining healthy weight in early menopause may help prevent VMS, a recent study found. Data from 10 follow-up visits for 1,546 participants in the Study of Women’s Health Across the Nation who reported no VMS at baseline were analyzed. Researchers found:

  • Greater concurrent BMI and waist circumference were significantly related to greater and frequent incident VMS in early menopause and lower VMS risk in late menopause.
  • Percentage weight change since baseline and since the prior visit was unrelated to incident VMS in either menopause stage.
  • Percentage weight change since baseline had a significant U-shaped association with incident frequent VMS in early menopause, a shallow inverse U-shape in late menopause, and a significant interaction with menopause stage, but not with race/ethnicity.
  • Recent weight change was not associated with incident VMS in either menopause stage.

Citation:

Gold EB, Crawford SL, Shelton, JF, et al. Longitudinal analysis of changes in weight circumference in relation to incident vasomotor symptoms: the Study of Women’s Health Across the Nation (SWAN). [Published online ahead of print October 3, 2016]. Menopause. doi:10.1097/GME.0000000000000723.