Clinical Edge

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Rescue Corticosteroids After Guideline Implementation

Obstet Gynecol; ePub 2017 Mar 6; Datkhaeva, et al

A high rate of rescue corticosteroids among eligible women was observed following implementation of an institutional guideline, a recent study found. The retrospective cohort study included 2,528 women who received an initial course of antenatal corticosteroids in the year before (2008) and in the 4 years (2009-2012) after implementation of an institutional guideline for their use. Researchers found:

  • 142 (5.6%) women were eligible for a rescue course of corticosteroids; 103 (73%) received it.
  • Rate of appropriate administration increased from 18.2% in 2008 to 65.4% in 2009, 93.5% in 2010, 96.1% in 2011, and 75.7% in 2012.
  • The rate of inappropriate administration among women ineligible for a rescue course (n=2,381) also rose during the study period.
  • 28% of all recipients of rescue corticosteroids were ineligible, according to the guideline.


Datkhaeva I, Dray D, Has P, Stifani B, Hughes BL, Rouse DJ. Uptake of a guideline for the administration of a rescue course of antenatal corticosteroids. [Published online ahead of print March 6, 2017]. Obstet Gynecol. doi:10.1097/AOG.0000000000001934.